Axle Informatics

Bioinformatics Scientist

Job Locations US-MD-Bethesda
Posted Date 2 months ago(2/15/2024 1:40 PM)
# of Openings


Axle Informatics is a bioscience and information technology company that offers advancements in translational research, biomedical informatics, and data science applications to research centers and healthcare organizations around the globe. With experts in biomedical science, software engineering, and program management, we focus on developing and applying research tools and techniques to empower decision-making and accelerate research discoveries. We work with some of the top research organizations and facilities in the country including multiple institutes at the National Institutes of Health (NIH). 


Axle is seeking multiple highly ambitious, adaptable, structured, and detail-oriented Bioinformatics Scientist to join our vibrant team at the National Institutes of Health (NIH), National Institute of Allergy and Infectious Diseases (NIAID), Division of Intramural Research (DIR), Research Technologies Branch (RTB), Integrated Data Sciences Section (IDSS) in Bethesda, MD.


  • Address bioinformatics, scientific computing, and data analysis needs of users within the Division of Intramural Research (DIR) at NIAID and their collaborators by lending expertise in the proper statistical design of biological experiments involving high-throughput genome-scale technologies, data mining and knowledge discovery techniques, automated workflow development, statistical and scientific experimental design consulting. Provide bioinformatics support to include somatic and germline variant calling and analysis, single-cell and bulk gene expression analysis, de novo assembly of genomes and transcriptomes, comparative genomics of model and non-model organisms, proteomics, ChIP-seq, ATAC-seq, and the development of high-throughput pipelines for the analysis of the above data modalities.
  • Provide programming and troubleshooting support to the Research Technologies Branch (RTB) of the National Institute of Allergy and Infectious Diseases (NIAID) and collaborating Institutes in the dissemination of research data. Perform computational data analysis on genomic and clinical research data. Work with staff on scientific programming and experimental design. Provide statistical support/analysis on research data. Contribute to and co-author scientific publications in leading peer-reviewed journals.
  • Contribute to the development of a scalable and flexible resource to provide NGS bioinformatics, structural biological and computational, machine learning data support to NIAID scientists and investigators. It is expected that the bioinformatics analysts will need strong skills in the following:
    • NGS analysis (whole-exome, whole-genome, RNA-seq, ChIP-Seq, both long- and short-read technologies, etc.) 
    • Statistical modeling
    • Scripting 
    • Biological interpretation


  • Minimum Bachelor’s degree in related field
  • Master’s or Ph.D. preferred
  • Four (4) years of experience in bioinformatics
  • Experience working in a laboratory setting is a plus
  • Expertise with Microsoft Office (Word, Excel, etc.)
  • Experience in R, Python, and other programming languages preferred


  • 100% Medical, Dental & Vision premium coverage for Employees  
  • Paid Time Off (Including Holidays)  
  • Employee Referral Bonus  
  • 401K Match  
  • Tuition reimbursement and professional development opportunities 
  • Flexible Spending Accounts: 
    • Healthcare (FSA) 
    • Parking Reimbursement Account (PRK) 
    • Dependent Care Assistant Program (DCAP) 
    • Transportation Reimbursement Account (TRN)


The diversity of Axle’s employees is a tremendous asset. We are firmly committed to providing equal opportunity in all aspects of employment and will not tolerate any illegal discrimination or harassment-based age, race, gender, religion, national origin, disability, marital status, covered veteran status, sexual orientation, status with respect to public assistance, and other characteristics protected under state, federal, or local law and to deter those who aid, abet, or induce discrimination or coerce others to discriminate. 


Accessibility: If you need an accommodation as part of the employment process please email: 


Disclaimer: The above description is meant to illustrate the general nature of work and level of effort being performed by individual’s assigned to this position or job description. This is not restricted as a complete list of all skills, responsibilities, duties, and/or assignments required. Individuals may be required to perform duties outside of their position, job description or responsibilities as needed.



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